Variation in Rate of Salicylate Elimination by Humans.
نویسندگان
چکیده
Although acute symptoms recurred during treatment in seven of the cases on aspirin, there was no evidence of recrudescence in the phenylbutazone group. REFERENCES Ablard, G., Larcan, A., and Welfringer, A. (1957). Un. m'd. Can., 86, 932. Begg, T. B., Kerr, J. W., and Knowles, B. R. (1962). Brit. med. 7., 2, 223. Chaptal, J., Jean, R., and Campo, C. (1956). Sem. Hop. Paris, 32, 1175. Colson, J. A., Uters, M., and Haberer, Ch. (1956). Bull. Soc. Mid. mflit. franQ., 50, 166. Currie. J. P. (1952). Lancet, 2, 15. Peebles Brown, R. A., and Will, G. (1953). Ann. rheum. Dis., 12, 88. Fleming, J., and Will, G. (1953). Ibid., 12, 95. Fletcher, A. A., Dauphinee, J. A., and Ogryzlo, M. A. (1952). 7. clin. Invest., 31, 561. Hitchens, R. A. N. (1956). Ann. rheum. Dis., 15, 160. Joint Report by M.R.C. and American Heart Association (1955). Brit. med. 7., 1, 555. Jones, T. D. (1944). 7. Amer. med. Ass., 126, 481. Kuzell, W. C., Schaffarzick, R. W., Naugler, W. E., Gaudin, G., and Mankle, E. A. (1953). Arch. intern. Med., 92, 646. Laplane, R., Debray, P., Salbreux, R., and Polonovski, C. (1957). Bull. Soc. Mid. Paris, 73, 302. Leff, S. (1956). Ann. rheum. Dis., 15, 33. Losner, S., and Volk, B. W. (1956). Amer. 7. med. Sci., 232, 276. Reid, J., and Sprouil, D. H. (1957). Brit. med. 7., 1, 1089. Stirland, R. M. (1956). Lancet, 1, 672. Welsh, J. D., Robinson, C., and Bird, R. M. (1961). Amer. 7. med. Sci., 241, 207. Will, G. (1958). Rheumatologie, 10, 103.
منابع مشابه
Effects of chronic exposure to dietary salicylate on elimination and renal excretion of salicylate by Drosophila melanogaster larvae.
The effects of chronic exposure to dietary salicylate on elimination and renal excretion of salicylate by D. melanogaster larvae were evaluated using salicylate-selective microelectrodes. Larvae chronically exposed to dietary salicylate showed 25% less salicylate in the haemolymph compared to the control group after feeding on a salicylate-enriched diet. By 1 h after transfer to a salicylate-fr...
متن کاملPharmacokinetics of Repeated Sodium Salicylate Administration to Laying Hens: Evidence for Time Dependent Increase in Drug Elimination from Plasma and Eggs
Salicylates were the first non-steroid anti-inflammatory drugs (NSAIDs) to be used in any species and are still widely used in humans and livestock. However, the data on their pharmacokinetics in animals is limited, especially after repeated administration. Evidence exist that in chickens (Gallus gallus) salicylate (SA) may induce its own elimination. The aim of this study was to investigate sa...
متن کاملAn evidence based flowchart to guide the management of acute salicylate (aspirin) overdose.
OBJECTIVE To develop a flowchart to be used as a tool to guide clinicians step by step through the management of salicylate poisoning. METHODS A comprehensive literature search was carried out. RESULTS The evidence base was used to develop a management flowchart that guides the clinician through the three main steps in caring for the patient with salicylate poisoning: preventing further abs...
متن کاملPlasma pharmacokinetics of pioglitazone following oral or intravenous administration in Holstein cows
Pioglitazone belongs to the thiazolidinedione (TZD) class of antidiabetic agents, with proven efficacy in increasing insulin sensitivity and in the treatment of type 2 diabetes mellitus in humans. Pioglitazone has been proposed as a potential feed additive to reduce insulin resistance and consequently some of the metabolic disorders in transition cows. This study was aimed at determining the ph...
متن کاملInvitro Release Study of Sodium Salicylate from Lecithin Based Phospholipid Microemulsions
Sodium salicylate containing microemulsions have been formulated, based on the previous phase diagram studies, using a pharmaceutically acceptable surfactant and oil. The effects of formulation variables on the release profile of the drug from microemulsion through intact rat skin were also determined experimentally. In this investigation, two commercially available lecithins (namely Epikuron 2...
متن کاملPercutaneous absorption of salicylic Acid after administration of trolamine salicylate cream in rats with transcutol(®) and eucalyptus oil pre-treated skin.
PURPOSE This study was conducted to assess the effect of skin pre-treatment with Transcutol(®) and eucalyptus oil on systemic absorption of topical trolamine salicylate in rat. METHODS Pharmacokinetic parameters of salicylic acid following administration of trolamine salicylate on rat skin pre-treated with either Transcutol(®) or eucalyptus oil were determined using both non-compartmental and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British medical journal
دوره 2 5404 شماره
صفحات -
تاریخ انتشار 1964